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Product introduction

NF-κB/MAPK-IN-1 (compound 11a) is a potent inhibitor of NF-κB and MAPK pathway. NF-κB/MAPK-IN-1 shows inhibitory activity against NO production, with an IC 50 of 6.96 µM. NF-κB/MAPK-IN-1 suppresses LPS-induced iNOS , COX-2 , ERΚ and P38 signaling activation. NF-κB/MAPK-IN-1 can prevent LPS induced inflammatory response in macrophages. NF-κB/MAPK-IN-1 can be used for rheumatoid arthritis (RA) research Form:Solid IC50& Target:NF-κB p38 COX-2

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Chinese name

NF-κB/MAPK-IN-1

English name

NF-κB/MAPK-IN-1

Chinese alias

English alias

CAS number

2413940-56-2

molecular formula

C27H27NO7

molecular weight

477.51 g/mol

Exact mass

≥98%

PSA

Logp

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