Share to
Overview
Specs
Technical Documents
Related
Articles
reviews
Consult
returns
Product introduction
BEZ235 (NVP-BEZ235, Dactolisib) ATP竞争性的抑制PI3K和mTOR,对p110α/γ/δ/β和mTOR(p70S6K)均有抑制作用,IC50分别为4 nM/5 nM/7 nM/75 nM/6 nM,对ATR也有抑制作用,IC50为21 nM;但对Akt和PDK1抑制作用微弱。A dual PI3K and mTOR inhibitor BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM, respectively. Inhibits ATR with IC50 of 21 nM, whileshown to be a poor inhibitor to Akt and PDK1. A dual PI3K and mTOR inhibitor
Chinese name
BEZ235,有效的PI3K和mTOR抑制剂, PI3 激酶 I 类抑制剂
English name
BEZ235
Chinese alias
-
English alias
BEZ235 | BEZ-235 | IRL-2500 is known as an ETB antagonist. | Lacidipinum | 2-methyl-2-(4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-1h-imidazo(4,5-c)quinolin-1-yl)phenyl)propanenitrile | AMY2877 | CT-BEZ | HY-50673 | NVP-BEZ235 | NVP-BEZ-235 | SCHEMBL105
CAS number
915019-65-7
molecular formula
C30H23N5O
molecular weight
469.54 g/mol
Exact mass
-
PSA
73.100 Ų
Logp
5.2
Technical Documents
「No technical documents」
Related
「No upstream and downstream information yet」
Articles
「No related articles yet」
user reviews
Loading...
Consultation

Warm reminder:

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.!

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ,We will handle it for you as soon as possible, thank you for your support and trust.!

NVP-BEZ235 98% 1g

NVP-BEZ235 98% 1g CAS 915019-65-7, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:N855207-1g
Product model:1g
level:
Lead Time:30days
sold 141 Items
Ask Solution engineer
Qty

Recommended for you