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Product introduction
AF3485 是一种人类 mPGES-1 抑制剂,显示出体外和体内的抗肿瘤活性。AF3485 通过减少 PGE2 产生,抑制EGFR信号传导,降低VEGF和 FGF-2 的表达,进而抑制肿瘤相关的血管生成。AF3485 在带有人类 A431 异种移植瘤的小鼠中,通过亚慢性给药减少了肿瘤生长。
Chinese name
n-[9-(2-Hydroxyethyl)-9h-carbazol-3-yl]-2-(trifluoromethyl)benzamide
English name
n-[9-(2-Hydroxyethyl)-9h-carbazol-3-yl]-2-(trifluoromethyl)benzamide
Chinese alias
-
English alias
-
CAS number
1195786-61-8
molecular formula
C22H17F3N2O2
molecular weight
398.38 g/mol
Exact mass
-
PSA
54.300 Ų
Logp
4.300
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n-[9-(2-Hydroxyethyl)-9h-carbazol-3-yl]-2-(trifluoromethyl)benzamide 1mg

n-[9-(2-Hydroxyethyl)-9h-carbazol-3-yl]-2-(trifluoromethyl)benzamide 1mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1mg.

item number:N953664-1mg
Product model:1mg
level: 1mg
Lead Time:30days
sold 358 Items
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Specifications:

1mg

Qty

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