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Org 48762-0, p38α/βinhibitor 10mg

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Product introduction
Org 48762-0 is a selective p38α and β kinase inhibitor (EC50 = 0.1 μM for p38α). Selective for p38α/β over a panel of 48 other human kinases. Inhibits LPS-induced TNFα release from PBMCs. Also inhibits cytokine release in an LPS-induced endotoxemia model in mice. Orally bioavailable.
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Chinese name
Org 48762-0,p38α/β抑制剂
English name
Org 48762-0
Chinese alias
4,6-双(4-氟苯基)-2-甲基-5-(4-吡啶基)-2H-吡唑并[3,4-b]吡啶
English alias
Org 48762-0 | SCHEMBL1386962 | 4,6-Bis(4-fluorophenyl)-2-methyl-5-(pyridin-4-yl)-2H-pyrazolo[3,4-b]pyridine | HY-114221 | 4,6-bis(4-fluorophenyl)-2-methyl-5-pyridin-4-ylpyrazolo[3,4-b]pyridine | 4,6-Bis(4-fluorophenyl)-2-methyl-5-(4-pyridyl)-2H-pyrazolo(3
CAS number
755753-89-0
molecular formula
C24H16F2N4
molecular weight
398.41 g/mol
Exact mass
≥98%
PSA
43.600 Ų
Logp
4.900
Technical Documents
「No technical documents」
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Org 48762-0, p38α/βinhibitor 10mg

Org 48762-0, p38α/βinhibitor 10mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10mg; ≥98%.

item number：O286758-10mg
Product model：10mg
level： 10mg; ≥98%
Lead Time：30days
sold 956 Items
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10mg

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