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Product introduction
羟基保泰松是保泰松通过在一个苯环的4位羟基化获得的代谢物。常以其水合物形式用于治疗关节炎和痛风相关的疼痛、肿胀和僵硬,但因与血液病和史蒂文斯-约翰逊综合征有关联,于1984年撤出市场。它具有抗菌剂、非甾体抗炎药、非麻醉性镇痛药、解热药、抗肿瘤药、痛风抑制剂、药物代谢物和外源性代谢物的作用。它是酚类和吡唑烷酮类的成员。它与保泰松功能相关。
Chinese name
羟布宗
English name
4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione
Chinese alias
羟基保泰松
English alias
G-27202 | NSC-757261 | Oxyphenbutazone [INN] | OXYPHENBUTAZONE ANHYDROUS, (+/-)- | Telidac | Metabolite I | Butilene | Flogodin | Genal | Ipabutona | Offitril | Ossifenbutazone | Butanora | Cinophen-N | Oxazolidin-Geigy | Neofen | Ossifenbutazone [DCIT] |
CAS number
129-20-4
molecular formula
C19H20N2O3
molecular weight
324.4
Exact mass
-
PSA
60.9
Logp
2.7
Safety
  • Human toxicity extract: 1960年至1966年间,有报道称使用保泰松或羟基保泰松治疗的 subjects 中出现了白血病病例。然而,现有证据不足以证明使用...与随后发生的白血病发展有关。
  • Other safety information: 化学品评估:IMAP评估 - 3,5-吡唑烷二酮,4-丁基-1-(4-羟基苯基)-2-苯基-:环境I级评估
  • Hazard categories and classifications: 水生急性1级(100%)
  • Non-human toxic extract: 狗长期肌肉注射3.6-35.2克苯丁唑酮10-103天后会产生胃溃疡。/苯丁唑酮/
  • Carcinogen Classification: IARC专著:第7卷补充:致癌性总体评价:IARC专著第1至42卷的更新,1987年;440页;ISBN 92-832-1411-0 (已绝版)
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
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Research chemical 100mg; ≥98%

Research chemical 100mg; ≥98%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 100mg; ≥98%.

item number:O342424-100mg
Product model:100mg
level: 100mg; ≥98%
Lead Time:30days
sold 202 Items
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100mg

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