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Product introduction

Oprozomib (ONX 0912)是一种口服生物有效的抑制剂，抑制20S proteasome（20S蛋白酶体）β5/LMP7的CT-L活性，IC50为36 nM/82 nM。 Oprozomib (ONX 0912) is an orally bioavailable inhibitor for CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM.

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Chinese name

Oprozomib (ONX 0912),抑制20S蛋白酶体β5/LMP7的CT-L活性, 26S 蛋白质体抑制剂

English name

Oprozomib (ONX 0912)

Chinese alias

奥泼佐米

English alias

ONX-0912 | PR-047 | J-690398 | N-((S)-3-methoxy-1-(((S)-3-methoxy-1-(((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)-2-methylthiazole-5-carboxamide | SWZXEVABPLUDIO-WSZYKNRRSA-N | DTXSID201025950

CAS number

935888-69-0

molecular formula

C25H32N4O7S

molecular weight

532.61 g/mol

Exact mass

PSA

176.000 Å²

Logp

1.1

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