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Product introduction

Olafertinib 是三代 EGFR 酪氨酸酶抑制剂，其GI50 值分别为5 nM (EGFR L858R/T790M)、10 nM (EGFR del19) 和 689 nM (EGFR WT)。 Olafertinib is a third-generation EGFR TKI, with GI50 values of 5 nM (EGFR L858R/T790M), 10 nM (EGFR del19) and 689 nM (EGFR WT), respectively. Olafertinib has the potential for NSCLC research.

Specs ⸢ View details ⸥

Chinese name

Olafertinib (RX-518)

English name

Olafertinib (RX-518)

Chinese alias

奥拉替尼 (RX-518)

English alias

CAS number

1660963-42-7

molecular formula

C29H28F2N6O2

molecular weight

530.57 g/mol

Exact mass

PSA

93.600 Å²

Logp

4.300

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