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Product introduction

PF-431396是双PYK2/FAK抑制剂，IC50分别为11nM和2 nM。 PF-431396 is a dual PYK2/FAK inhibitor with IC50 of 11 nM and 2 nM, respectively. A dual inhibitor of FAK (focal adhesion kinase) and PYK2.

Specs ⸢ View details ⸥

Chinese name

PF-431396

English name

PF-431396

Chinese alias

English alias

CCG-221509 | s7644 | DTXSID50469204 | BDBM50246060 | HY-10460 | N-methyl-N-{2-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]phenyl}methanesulfonamide | HMS3244D08 | EX-A787 | NCGC00370948-06 | PF431396 | PF-4

CAS number

717906-29-1

molecular formula

C22H21F3N6O3S

molecular weight

506.5 g/mol

Exact mass

10mM in DMSO

PSA

125.000 Å²

Logp

2.800

Technical Documents

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