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Product introduction
PF 6274484 is a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM. PF 6274484 inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and 6.6 nM, respectively.
Chinese name
PF 6274484,共价EGFR激酶抑制剂
English name
PF 6274484
Chinese alias
N-[4-[(3-氯-4-氟苯基)氨基] -7-甲氧基-6-喹唑啉基] -2-丙烯酰胺
English alias
PF-6274484 | N-4-(3-Chloro-4-fluorophenyl)amino-7-methoxy-6-quinazolinyl-2-propenamide | N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide
CAS number
1035638-91-5
molecular formula
C18H14ClFN4O2
molecular weight
372.78 g/mol
Exact mass
≥98%(HPLC)
PSA
76.100 Ų
Logp
3.900
Technical Documents
「No technical documents」
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Research chemical 10mg; ≥98%; HPLC

Research chemical 10mg; ≥98%; HPLC; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 10mg; ≥98%; HPLC.

item number:P288199-10mg
Product model:10mg
level: 10mg; ≥98%; HPLC
Lead Time:30days
sold 488 Items
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Specifications:

10mg

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