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Product introduction

PF-04217903是一种选择性的，ATP竞争性c-Met抑制剂，IC50为4.8 nM，对致癌基因突变型敏感(对Y1230C突变型没有活性)。A selective ATP-competitive Met inhibitor. PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susceptible to oncogenic mutations (no activity to Y1230C mutant). A selective ATP-competitive Met inhibitor.

Specs ⸢ View details ⸥

Chinese name

PF-04217903, 肝细胞生长因子受体抑制剂

English name

PF-04217903

Chinese alias

English alias

2-(4-(3-(quinolin-6-ylmethyl)-3H-[1,2,3]triazolo[4,5-b]pyrazin-5-yl)-1H-pyrazol-1-yl)ethanol | 2-[4-[1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazol-1-yl]ethanol | HY-12017 | PF-4217903 | AC-35476 | AKOS040732470 | MFCD12407410 |

CAS number

956905-27-4

molecular formula

C19H16N8O

molecular weight

372.38 g/mol

Exact mass

≥98%

PSA

107.000 Å²

Logp

0.7

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