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Product introduction

PHT-427是作用于Akt和PDPK1的双重抑制剂，Akt和PDPK1的PH结构域具有高度亲和力，Ki分别为2.7 μM和5.2 μM。A pleckstrin homology domain inhibitor to Akt and PKB Kinase (PDPK1). PHT-427 is a dual Akt and PDPK1 inhibitor (high affinity binding for the PH domains of Akt and PDPK1) with Ki of 2.7 μM and 5.2 μM, respectively A pleckstrin homology domain inhibitor to Akt and PKB Kinase (PDPK1).

Specs ⸢ View details ⸥

Chinese name

PHT-427,双Akt和PDK1抑制剂, 3-磷酸肌酸依赖性蛋白激酶 1 抑制剂

English name

PHT-427

Chinese alias

English alias

J-515259 | PHT427 | PHT-427 | HB1251 | AS-69526 | AC-30264 | CCG-268762 | SB17376 | BP-30156 | BYWWNRBKPCPJMG-UHFFFAOYSA-N | J-004083 | HY-12063 | 4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide | 4-Dodecyl-N-1,3,4-thiadiazol-2-yl-benzenesulfonamide |

CAS number

1191951-57-1

molecular formula

C20H31N3O2S2

molecular weight

409.61 g/mol

Exact mass

PSA

109.000 Å²

Logp

7.400

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