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Product introduction

PF-04457845是FAAH选择性抑制剂，IC50为7.2 nM，具有镇痛和抗炎活性。 PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen.

Specs ⸢ View details ⸥

Chinese name

PF-04457845,不可逆FAAH抑制剂, 安乃近酰胺水解酶抑制剂

English name

PF-04457845

Chinese alias

English alias

N-pyridazin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzylidene)piperidine-1-carboxamide | s2421 | HY-14376 | N-Pyridazin-3-yl-4-((3-(5-(trifluoromethyl)pyridin-2-yl)oxyphenyl)methylidene)piperidine-1-carboxamide | PF04457845 | PF-04457845 | AC-36

CAS number

1020315-31-4

molecular formula

C23H20F3N5O2

molecular weight

455.43 g/mol

Exact mass

PSA

80.200 Å²

Logp

3.3

Technical Documents

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