Share to

Overview

Specs

Technical Documents

Articles

reviews

Consult

returns

Product introduction

Purmorphamine与Smo拮抗剂竞争性结合到Smoothened，并激活Smoothened，IC50约为1.5 μM，也诱导成骨细胞分化，EC50为1μM。An activator of the hedgehog (Hh) signaling pathway. Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM and also is an inducer of osteoblast differentiation with EC50 of 1 μM. An activator of the hedgehog (Hh) signaling pathway.

Specs ⸢ View details ⸥

Chinese name

Purmorphamine,平滑受体激动剂, SMO 的激动剂

English name

Purmorphamine

Chinese alias

9-环己基-N-[4-(4-吗啉基)苯基]-2-(1-萘氧基)-9H-嘌呤-6-胺 | 2-（1-萘基）-6-（4-吗啉苯胺）-9-环己嘌呤

English alias

Shh Signaling Antagonist VI | 2-(1-Naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine

CAS number

483367-10-8

molecular formula

C31H32N6O2

molecular weight

520.62 g/mol

Exact mass

PSA

77.300 Å²

Logp

6.500

Technical Documents

「No technical documents」

「No upstream and downstream information yet」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！