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Product introduction
PP1是一种有效的Src选择性抑制剂,作用于Lck/Fyn时,IC50为5 nM/6 nM。 Application: PP1 has been used as: an inhibitor of sarcoma (Src) family kinases (SFK) like hematopoietic cell kinase (hck) and fyn a selective Src tyrosine kinase inhibitor in hippocampal neuronal cultures to test its effect on neurite growth a Src-kinase blocker to test its effect on brimonidine (BMD)-induced phosphorylation in extracellular signal-activated kinases(ERK1/2) PP1 is a potent and selective Src inhibitor for Lck/Fyn with IC50 of 5 nM/ 6 nM. A selective and potent Src family tyrosine kinase inhibitor.
Chinese name
PP1, C 端 Src 激酶抑制剂
English name
1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-amine
Chinese alias
-
English alias
1-(tert-Butyl)-3-(p-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 12L-341S | 4-AMINO-1-TERT-BUTYL-3-(4-METHYLPHENYL)PYRAZOLO[3,4-D]PYRIMIDINE | HMS3652F20 | HMS2191A04 | KBio2_002942 | MLS000326642 | PP1 | PP-1 | 1-tert-butyl-3-(p-tolyl)-1h-pyrazolo[3,4-d]
CAS number
172889-26-8
molecular formula
C16H19N5
molecular weight
281.36
Exact mass
-
PSA
69.6
Logp
2.8
Technical Documents
「No technical documents」
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PP1 10mM in DMSO 1ml

PP1 10mM in DMSO 1ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1ml.

item number:P580479-1ml
Product model:1ml
level: 1ml
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