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Product introduction

PF-03654746 是一种有效的选择性组胺 H3 receptor 拮抗剂，具有脑渗透性。PF-03654746 可减少过敏原引起的鼻炎反应。PF-03654746 Tosylate (PF-03654746)可以用于人类认知障碍，改善阿尔茨海默症 (AD) 的相关研究。 PF-03654746 is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 reduces allergen-induced nasal symptoms, might be a novel therapeutic strategy to further explore allergic rhinitis. PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD)

Specs ⸢ View details ⸥

Chinese name

PF-03654746, 组胺 H3 受体拮抗剂

English name

PF-03654746

Chinese alias

compound 6 | PF 03654746 | PF03654746

English alias

N-ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]cyclobutane-1-carboxamide | G3QE979K1X

CAS number

935840-31-6

molecular formula

C18H24F2N2O

molecular weight

322.39 g/mol

Exact mass

PSA

32.299 Å²

Logp

2.5

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