
- Toxicity summary: 丙哌嗪是1型、2型和4型多巴胺受体、血清素(5-HT)受体2A和2C型、毒蕈碱受体1至5型、α(1)-受体和组胺H1-受体的拮抗剂。其主要用作镇静剂是由于其抗组胺作用。
- interaction: 先前单独给予东莨菪碱或联合给予美哌啶和丙嗪的17名产妇给予了毒扁豆碱,以确定其对逆转胎儿心率变异性丧失的影响。在使用美哌啶和丙嗪联合治疗时,10名患者出现了逆转。
- Health Effects: 它们会导致言语不清、定向障碍和"醉酒"行为。它们具有生理和心理成瘾性。
- Symptoms and Signs: 罕见但严重的副作用包括惊厥(癫痫);呼吸困难或呼吸过快;心跳或脉搏快速或不规则;发热(高烧);血压高或低;膀胱控制丧失;肌肉僵硬(严重);出汗异常增加;皮肤异常苍白;以及异常疲劳或虚弱。
- Hazard categories and classifications: 水环境慢性2(100%)
- Carcinogen Classification: 对人类无致癌性迹象(未被IARC列出)。
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Research chemical 5mg; ≥95%
Research chemical 5mg; ≥95%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg; ≥95%.
5mg




