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Product introduction

PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1) , with no effect on PTH type 2 receptor. In Vitro PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor. PCO371 induces cAMP production with an EC 50 of 2.4 μM in COS-7 cells expressing hPTHR1, and 2.5 μM in COS-7 cells transfected with hPTHR1-delNT, and also enhances the phospholipase C activity (EC 50 , 17 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PTHR1

Specs ⸢ View details ⸥

Chinese name

PCO371

English name

PCO371

Chinese alias

English alias

EX-A2839 | DB14946 | HY-100856 | BCP31012 | SB19668 | MS-30887 | AKOS040742371 | UNII-TE53TU0WSQ | SCHEMBL17104864 | PCO371 | PCO-371 | GTPL12788 | LDZJFVOUPUFOHX-UHFFFAOYSA-N | PC-0371 | BDBM64562 | US9428505, Compound 7 | AC-31576 | 2,4-Imidazolidinedio

CAS number

1613373-33-3

molecular formula

C29H32F3N5O6S

molecular weight

635.65 g/mol

Exact mass

≥98%

PSA

146.000 Å²

Logp

3.700

Technical Documents

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