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Product introduction
PIK-75游离碱是PI 3-激酶p110α的选择性抑制剂(PI 3-激酶p110α,PI 3-激酶p110γ和PI 3-激酶p110β的IC50值分别为5.8、76 nM和1.3μM)。抑制脂肪细胞中PIP2和PIP3的产生,Akt的磷酸化以及mTORC1的激活。细胞可渗透的。 PIK-75, free base is a selective inhibitor of PI 3-kinase p110α (IC50 values are 5.8, 76 nM and 1.3 μM at PI 3-kinase p110α, PI 3-kinase p110γ and PI 3-kinase p110β respectively). Inhibits production of PIP2 and PIP3 in adipocytes, phosphorylation of Akt and activation of mTORC1. Cell-permeable.
Chinese name
PIK-75,游离, 磷脂酰肌醇-4
English name
PIK-75, free base
Chinese alias
-
English alias
N'-[(1E)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide hydrochloride | DS-15894 | N-[(E)-(6-Bromoimidazo[1,2-a]pyridin-3-yl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamide | NCGC00346500-05 | UNII-9058I
CAS number
372196-67-3
molecular formula
C16H14BrN5O4S
molecular weight
452.28 g/mol
Exact mass
-
PSA
121.000 Ų
Logp
3.800
Technical Documents
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PIK-75 free base 95% 25mg

PIK-75 free base 95% 25mg Macklin 372196-67-3, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:P787445-25mg
Product model:25mg
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Lead Time:30days
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