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Product introduction
PF-06840003 (EOS200271) 是一种选择性 IDO-1 抑制剂,抑制 hIDO-1, dIDO-1,和 mIDO-1 的IC50 分别为 0.41 μM, 0.59 μM,和 1.5 μM。 尽管它对hIDO1仅具有中等抑制作用(IC50=0.41 μM),但它能与hIDO-1紧密结合,和hIDO-1之间形成高密度的氢键,所以PF-06840003是一个非常高效的化合物(LE 0.53, LipE 5.1)。
Chinese name
PF-06840003,IDO-1 抑制剂, 吲哚胺 2
English name
PF-06840003
Chinese alias
-
English alias
AKOS027252536 | EOS200271 | EOS-200271 | Q420698 | US9603836, Compound 1 | GTPL9565 | A925049 | s8657 | SCHEMBL5463464 | EOS200271; EOS-200271; EOS 200271; PF 06840003; PF06840003 | EX-A1186 | NSC-796100 | BP168137 | DTXSID00630149 | SB22834 | AMY445 | 2,
CAS number
198474-05-4
molecular formula
C12H9FN2O2
molecular weight
232.21 g/mol
Exact mass
-
PSA
62.000 Ų
Logp
0.900
Technical Documents
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PF-06840003 10mM in DMSO 1ml

PF-06840003 10mM in DMSO 1ml Macklin 198474-05-4, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:P794991-1ml
Product model:1ml
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Lead Time:30days
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