PAMAM树状聚合物是一种具有大量末端基团的对称聚合物，由于其生物相容性和亲和性，可以轻易地与生物分子结合。这些树枝状聚合物具有多价表面，其中包含包膜和与树枝相附的核内各种活性位点。它们是高度分支的纳米级聚合物，广泛用于在生物医学领域的靶向给药。 应用 PAMAM树状聚合物可作为核酸递送的转染剂使用。例如，它可用于靶向肿瘤坏死因子(TNF)的siRNA的肺部给药。 PAMAM dendrimer is a symmetrical polymer with a large number of terminal groups that can easily bind to biomolecules due to their biocompatibility and affinity. These dendrimers have a multivalent surface that contains envelopes and various active sites at the core with the attached dendrons. They are highly branched nanoscale polymers that are extensively used in the field of biomedicine for targeted drug delivery. Application PAMAM dendrimers can be used as transfection agents for the delivery of nucleic acids. For example, it can be used in the pulmonary delivery of siRNA directed against tumor necrosis factor (TNF).