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Product introduction
PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC based on Cereblon ligand, which potently and selectively induces the degradation of Bcl-2 ( IC 50 , 4.94 μM; DC 50 , 3.0 μM) and Mcl-1 ( IC 50 , 11.81 μM) by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1/Bcl-2 dual inhibitor Nap-1 Form:Solid IC50& Target:Bcl-2 3 μM (DC 50 ) Bcl-2 4.94 μM (IC 50 ) Mcl-1 11.81 μM (IC 50 )
Chinese name
PROTAC Bcl2 degrader-1
English name
PROTAC Bcl2 degrader-1
Chinese alias
PROTAC Bcl2降解剂-1
English alias
-
CAS number
2378801-85-3
molecular formula
C45H45BrN6O10S
molecular weight
941.84 g/mol
Exact mass
≥98%
PSA
235.000 Ų
Logp
4.300
Technical Documents
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PROTAC Bcl2 degrader-1 98% 1mg

PROTAC Bcl2 degrader-1 98% 1mg CAS 2378801-85-3, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:P937074-1mg
Product model:1mg
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Lead Time:30days
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