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Product introduction
Poloppin 是一种有效的细胞渗透抑制剂,可抑制有丝分裂的 polo 样激酶 (PLK) (IC50=26.9 μM),并可通过Polo-box 结构域 (PBD) 阻止蛋白之间的相互作用 (Kd= 29.5 μM)。Poloppin 选择性地杀死表达突变 KRAS 的细胞,增强有丝分裂中的死亡。Poloppin 可用作 KRAS 突变型癌症的研究,可作为单一试剂,或与 c-MET 抑制剂联合使用。
Chinese name
Poloppin
English name
Poloppin
Chinese alias
-
English alias
-
CAS number
683808-78-8
molecular formula
C20H15BrF3NO2
molecular weight
438.24 g/mol
Exact mass
-
PSA
42.200 Ų
Logp
5.400
Technical Documents
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Consultation

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Poloppin 1mg

Poloppin 1mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1mg.

item number:P975634-1mg
Product model:1mg
level: 1mg
Lead Time:30days
sold 559 Items
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Specifications:

1mg

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