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Product introduction

Roflumilast is a selective phosphodiesterase 4 (PDE4) (IC50 = 0.8 nM) inhibitor. Inhibition of PDE4 prevents the hydrolysis of phosphodiesters, which play a key role in signal transduction. This compound has anti-inflammatory properties and is particularly effective at reducing inflammation in lung tissue.A selective inhibitor of phosphodiesterase 4 Roflumilast is a selective phosphodiesterase 4 (PDE4) (IC50 = 0.8 nM) inhibitor. Inhibition of PDE4 prevents the hydrolysis of phosphodiesters, which play a key role in signal transduction. This compound has anti-inflammatory properties and is particularly effective at reducing inflammation in lung tissue. A selective inhibitor of phosphodiesterase 4

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Chinese name

罗氟司特, 磷酸二酯酶 4 抑制剂

English name

Roflumilast

Chinese alias

罗氟司特

English alias

DTXSID8044123 | ROFLUMILAST [JAN] | BYK 20869 | BYK20869 | BYK-20869 | MLS006010074 | Roflumilast (Daxas) | ROFLUMILAST (MART.) | 0P6C6ZOP5U | ROF | SY008710 | PB29130 | UNII-0P6C6ZOP5U | ZORYVE | 1xmu | 3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)

CAS number

162401-32-3

molecular formula

C17H14Cl2F2N2O3

molecular weight

403.21 g/mol

Exact mass

PSA

60.500 Å²

Logp

4.6

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