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Product introduction

RO2959 monohydrochloride 是一种有效的选择性 CRAC 通道抑制剂，IC50 为 402 nM。RO2959 monohydrochloride 是由 Orai1/Stim1 通道介导的钙存储进入 (SOCE) 的有效阻滞剂，IC50 为 25 nM。RO2959 monohydrochloride 还是人 IL-2 产生的有效抑制剂，有效阻断 T 细胞受体触发的基因表达和 T 细胞功能途径。 Information RO2959 hydrochloride is a potent and selective inhibitor of CRAC channel with IC50 of 402 nM. RO2959 hydrochloride is also a potent inhibitor of human IL-2.

Specs ⸢ View details ⸥

Chinese name

RO2959盐酸盐

English name

RO2959 hydrochloride

Chinese alias

English alias

RO2959 HCl

CAS number

1219927-22-6

molecular formula

C21H20ClF2N5OS

molecular weight

463.93 g/mol

Exact mass

PSA

99.300 Å²

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