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Product introduction

Rhosin hydrochloride 是一种有效的，特异性的 RhoA 亚家族 Rho GTPases 抑制剂，能特异性的结合 RhoA，抑制 RhoA-GEF 相互作用，Kd 值 ~ 0.4 uM，但不与 Cdc42 或 Rac1，GEF，LARG 相互作用。Rhosin hydrochloride 可诱导细胞凋亡。Rhosin hydrochloride 通过增强 D1 中棘神经元的可塑性和降低过度兴奋性来促进应激恢复。

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Chinese name

Rhosin hydrochloride

English name

Rhosin hydrochloride

Chinese alias

D-色氨酸(2E)-2-(6-喹喔啉基亚甲基)酰肼盐酸盐 | 盐酸松香

English alias

D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide hydrochloride | (R,E)-2-amino-3-(1H-indol-3-yl)-N'-(quinoxalin-6-ylmethylene)propanehydrazide hydrochloride | G04 hydrochloride | Rhosin HCl

CAS number

1281870-42-5

molecular formula

C20H19ClN6O

molecular weight

394.86 g/mol

Exact mass

10mM in DMSO

PSA

109.000 Å²

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