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Product introduction

Relacorilant 是一种有效的，选择性的糖皮质激素受体 (glucocorticoid receptor) 拮抗剂，在 HepG2 TAT 实验中，Ki 值为 7.2 nM，在细胞体系中，对大鼠，人和猴子糖皮质激素受体的 Ki 值分别为 12，81.2，210 nM；Relacorilant 有潜力用于库欣综合征的研究。

Specs ⸢ View details ⸥

Chinese name

Relacorilant, 糖皮质激素受体拮抗剂

English name

Relacorilant

Chinese alias

雷科瑞兰

English alias

Relacorilant | BDBM50265673 | Methanone, ((4aR)-1-(4-fluorophenyl)-1,4,5,6,7,8-hexahydro-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4ah-pyrazolo(3,4-g)isoquinolin-4a-yl)(4-(trifluoromethyl)-2-pyridinyl)- | (R)-(1-(4-fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)

CAS number

1496510-51-0

molecular formula

C27H22N6O3F4S

molecular weight

586.6 g/mol

Exact mass

PSA

111.000 Å²

Logp

2.9

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