- Interactions： ...Mice were treated orally with ciprofloxacin (50 mg/kg) alone, the iron compound (ferrous sulphate, sodium ferrous citrate or ferric pyrophosphate; 50 mg elemental iron/kg) alone, ciprofloxacin with each iron compound or ciprofloxacin in combination with each iron compound and ascorbic acid (250 mg/kg). The maximum serum concentration of ciprofloxacin was significantly (P<0.01) reduced from 1.15+/-0.11 ug/mL (ciprofloxacin alone) to 0.17+/-0.01, 0.27+/-0.01 or 0.28+/-0.02 ug/mL, respectively, when ferrous sulphate, sodium ferrous citrate or ferric pyrophosphate was administered along with ciprofloxacin. The addition of ascorbic acid did not affect the inhibitory effects of each iron compound on the absorption of ciprofloxacin. Ciprofloxacin did not affect the variation of serum iron l...
- Hazards Summary： May cause irritation; [MSDSonline] See Iron oxide (Fe2O3).
- Primary Hazards： Not Classified
- Disposal Methods： The following wastewater treatment technologies have been investigated for iron (Fe+2): Concentration process: Biological treatment. /Iron (Fe+2)/
- FDA Requirements： Ferric pyrophosphate used as a nutrient and/or dietary supplement in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
- Preventive Measures： All ... /iron/ preparations should be kept in child-proof bottles. /Iron preparations/
- Regulatory Information： New Zealand EPA Inventory of Chemical Status: Diphosphoric acid, iron(3+) salt (3:4): Does not have an individual approval but may be used under an appropriate group standard
- Other Safety Information： Chemical Assessment: IMAP assessments - Diphosphoric acid, iron(3+) salt (3:4): Human health tier I assessment
- Non-Human Toxicity Excerpts： /GENOTOXICITY/ A number of ferrous and ferric salts have been tested for mutagenicity using the following organisms. Saccharomyces cerevisiae strain D-4, Salmonella typhimurium strains. TA-1535, TA-1537, and TA-1538 with and without activation. Plate tests as well as suspension tests were run with the Salmonella strains. ...Ferric pyrophosphate... /was/ inactive in all the systems used.
- Populations at Special Risk： ...There is concern that the individual with metabolic defects that impair the ability to regulate iron absorption will be at risk from excessive exposure to iron, primarily as a result of acceleration of accumulation of iron in the body and an earlier onset of clinical symptoms of the disease. /Iron salts/
- Hazard Classes and Categories： Not Classified
- State Drinking Water Standards： (NC) NORTH CAROLINA 300 ug/L /Iron/
- State Drinking Water Guidelines： (ME) MAINE 340 ug/L /Iron/
- Antidote and Emergency Treatment： Hemodialysis and hemoperfusion are not effective for removing iron but may be necessary to remove iron-deferoxamine complex in patients with renal failure. Exchange transfusion is occasionally used for massive pediatric ingestions but is of questionable efficacy.
- Federal Drinking Water Guidelines： EPA 300 ug/L /Iron/
- Skin, Eye, and Respiratory Irritations： If inhaled, iron is a local irritant to the lung and gastrointestinal tract. /Iron compounds/
- Other Standards Regulations and Guidelines： Australia (1978); Belgium (1978); Finland (1975); Italy (1978); Netherlands (1978); and Switzerland (1978): 1 mg/cu m. /From table/ /Ferric salts, as Fe/
Warm reminder：
Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！
Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.
Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！
Research chemical CAS 10058-44-3 98% 25g
Yuanye Research chemical CAS 10058-44-3 98% 25g, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
