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Product introduction

ST638是一种蛋白质酪氨酸激酶抑制剂（IC | 50 | = 370 nM），也可以抑制HGF诱导的肝细胞中MAP激酶激活。ST638还显示出抑制人类嗜中性粒细胞中PC-PLD（磷脂酶D）的活性。该产品减少了中性粒细胞中过钒酸盐诱导的O2⋅产生。 ST638 is a protein tyrosine kinase inhibitor (IC|50|= 370 nM) that also inhibits HGF-induced MAP kinase activation in hepatocytes. ST638 has also shown to inhibit PC-PLD (phospholipase D) activity in human neutrophils. This product decreases the O2? production induced by pervanadate in neutrophils.

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Chinese name

ST638

English name

2-cyano-3-[3-ethoxy-4-hydroxy-5-(phenylsulfanylmethyl)phenyl]prop-2-enamide

Chinese alias

English alias

CAS number

107761-24-0

molecular formula

C19H18N2O3S

molecular weight

354.4

Exact mass

PSA

122

Logp

3.1

Safety

Hazard categories and classifications：急性毒性 4 (100%)

Technical Documents

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Consultation

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