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Product introduction

SRI 31215 是 matriptase、hepsin、肝细胞生长因子激活剂(HGFA)的三重抑制剂，IC50值分别为 0.69 μM、0.65 μM、0.3 μM。它能够阻断 pro-HGF 的活化，模拟 HAI-1/2 的活性。 SRI 31215, a small molecule that acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation with IC50s of 0.69 μM, 0.65 μM, 0.3 μM.

Specs ⸢ View details ⸥

Chinese name

SRI 31215 TFA

English name

SRI 31215 TFA

Chinese alias

English alias

SRI 31215

CAS number

1832686-44-8

molecular formula

C27H34F3N5O3

molecular weight

533.59 g/mol

Exact mass

≥98%

PSA

Logp

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