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Product introduction

Information SBC-115076 SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 ( PCSK9 ) antagonist. Targets PCSK9 In vitro In HepG2 cells, SBC-115076 increases the uptake of Fluorescent Dil-LDL. In vivo In mice that are fed high fat diet, SBC-115076 (8 mg/kg) lowers cholesterol levels by 32%.

Specs ⸢ View details ⸥

Chinese name

SBC-115076

English name

SBC-115076

Chinese alias

English alias

4-(4-(benzyloxy)-3-methylbenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one

CAS number

489415-96-5

molecular formula

C31H33N3O5

molecular weight

527.61 g/mol

Exact mass

≥98%

PSA

92.200 Å²

Logp

3.700

Technical Documents

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