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Product introduction
LY2874455是一个泛FGFR的抑制剂,对FGFR1,FGFR2, FGFR3, 和FGFR4的IC50值分别为2.8 nM, 2.6 nM, 6.4 nM,以及6 nM。并且也能抑制VEGFR2的活性,IC50为7 nM。Phase 1。 LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM. Phase 1.
Chinese name
LY2874455,FGF / FGFR抑制剂, 成纤维细胞生长因子受体 1 抑制剂
English name
LY2874455
Chinese alias
-
English alias
7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one | C18374 | (R,E)-2-(4-(2-(5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethan-1-ol | BCP04756 | LY2874455 | LY-2874455 | BCP0726000015 |
CAS number
1254473-64-7
molecular formula
C21H19Cl2N5O2
molecular weight
444.31 g/mol
Exact mass
-
PSA
88.900 Ų
Logp
3.500
Technical Documents
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LY2874455 98% 10mg

Yuanye LY2874455 98% 10mg, CAS 1254473-64-7, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S41732-10mg
Product model:10mg
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Lead Time:30days
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