对甲苯磺酰甲基异腈在微波辐射下与固定化亚胺进行碱促进的1,3-偶极环加成反应，得到1,5-二取代咪唑。它是有机化学中的多功能合成子，广泛用于杂环化合物的合成。 用途 对甲基苯磺酰甲基异腈： 用于具有1,3,5-三氧杂环己烷骨架的三联体药物的合成中 用作制备生物活性吡咯和咪唑的试剂 用作使用糖衍生醛的非对映选择性雀形目反应中的异腈组分 Product Introduction p-Toluenesulfonylmethyl isocyanide undergoes base-promoted 1,3-dipolar cycloaddition reaction with immobilized imines under microwave irradiation to yield 1,5-disubstituted imidazoles. It is a versatile synthon in organic chemistry, extensively used for the synthesis of heterocyclic compounds. Application p-Toluenesulfonylmethyl isocyanide was used: in the synthesis of triplet drugs with the 1,3,5-trioxazatriquinane skeleton as reagent in the preparation of biologically active pyrroles and imidazoles as the isonitrile component in a diastereoselective Passerini reaction employing sugar-derived aldehydes