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Product introduction

Neratinib (HKI-272)是一种高度选择性的HER2和EGFR抑制剂，IC50分别为59 nM和92 nM；微弱抑制KDR和Src，对Akt，CDK1/2/4， IKK-2， MK-2， PDK1， c-Raf和c-Met没有显著的抑制作用。Phase 3。 Neratinib (HKI-272) is a highly selective HER2 and EGFR inhibitor with IC50 of 59 nM and 92 nM; weakly inhibits KDR and Src, no significant inhibition to Akt, CDK1/2/4, IKK-2, MK-2, PDK1, c-Raf and c-Met. Phase 3. A potent and selective inhibitor of EGFR and HER2

Specs ⸢ View details ⸥

Chinese name

Neratinib (HKI-272), 受体蛋白-酪氨酸激酶 erbB-4 抑制剂

English name

Neratinib (HKI-272)

Chinese alias

来那替尼 | 来那替尼 (HKI-272)

English alias

EC 244-343-6 | N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide | CHEBI:61397 | N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide |

CAS number

698387-09-6

molecular formula

C30H29ClN6O3

molecular weight

557.04 g/mol

Exact mass

PSA

112.000 Å²

Logp

4.9

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Neratinib (HKI-272) 98% 5mg

Name: Neratinib (HKI-272) 98% 5mg
Brand: 上海源叶
SKU: S49915-5mg

Yuanye Neratinib (HKI-272) 98% 5mg, CAS 698387-09-6, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：S49915-5mg

Product model：5mg

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Lead Time：30days

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Neratinib (HKI-272) 98% 5mg

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