[1,4-Bis(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate is a rhodium-based catalyst used for regioselective hydrogenation and enantioselective reductive amination reactions. Application： [1,4-Bis(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I)tetrafluoroborate can be used as a catalyst for the: Regioselective hydrogenation of thebaine to synthesize tetrahydrothebaine. Enantioselective reductive amination of α-ketoacids with benzylamines to synthesize α-N-benzylamino acids. Stereoselective hydrogenation of α-(hydroxymethyl)-acrylate derivatives to synthesize 3-hydroxy-2-methylpropanoates.