- Harmful effect： 已有药物性胆汁淤积和肝毒性报道。
- Toxicity summary： 美托拉酮没有解毒剂。应尽快采取支持措施以维持水合、电解质平衡、呼吸以及心血管和肾功能。由于其高血浆蛋白结合率，透析无法将其去除。拨打美国毒物控制中心(800-222-1222)获取有关特定过量管理的最新信息。
- Human toxicity extract： 不良反应...紫癜，光敏性，皮疹，荨麻疹，坏死性血管炎，发热，呼吸窘迫，过敏反应，高血糖，糖尿，高尿酸血症，肌肉痉挛，虚弱，烦躁，视力模糊，&血尿。/噻嗪类/
- non-human toxicity value： LD50 小鼠腹腔注射 > 1500 MG/KG
- Hazard categories and classifications： STOT SE 3 (100%)
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation： 截至修订日期，未找到美托拉宗的相关已发表信息。噻嗪类和噻嗪样利尿剂、限制液体摄入和乳房压迫已被用于抑制产后泌乳。这些有效的泌乳抑制措施中增加利尿剂的作用尚未研究。关于利尿剂对已建立的持续泌乳的影响尚无数据。
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Research chemical CAS 17560-51-9 1ml
Yuanye Research chemical CAS 17560-51-9 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
