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Product introduction

Solabegron (GW 427353) 是一种β3肾上腺素能受体 (β3-AR)的选择性激动剂, 在中国仓鼠卵巢细胞中测得 EC50=22 nM，可用于研究膀胱过度活跃和肠易激综合征。 Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome.

Specs ⸢ View details ⸥

Chinese name

solabegron, β-3 肾上腺素能受体激动剂

English name

solabegron

Chinese alias

索拉贝隆

English alias

CAS number

252920-94-8

molecular formula

C23H23ClN2O3

molecular weight

410.89 g/mol

Exact mass

PSA

81.600 Å²

Logp

1.8

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