- Harmful effect： 尿中的索他洛尔在使用荧光法或光度法测量时可能导致尿中变肾上腺素水平假性升高。
- Toxicity summary： 最近的研究评估了急性药物过量后药物特异性严重QT延长（SQTP）风险。索他洛尔是与SQTP相关的急性药物过量中最常见的药物之一。根据美国毒物控制中心协会的循证共识，摄入索他洛尔超过4 mg/kg表示需要转诊至急诊科。对于无意中摄入索他洛尔的无症状患者，建议至少观察12小时。根据EXTRIP（中毒体外治疗）指南，索他洛尔可透析。体外治疗的指征包括难治性心动过缓、反复性尖端扭转型室速和低血压。
- Hepatotoxicity： 可能性评分：E（不太可能引起明显的肝损伤）。
- Hazard categories and classifications： 特定靶器官毒性-重复接触 1级 (100%)
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation： 截至修订日期，未找到关于正常哺乳期间β阻滞或索他洛尔效应的相关已发表信息。一项对6名高催乳素血症和溢乳患者的研究发现，使用普萘洛尔进行β肾上腺素能阻滞后，血清催乳素水平没有变化。
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Research chemical 5mg; ≥98%
Research chemical 5mg; ≥98%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg; ≥98%.
5mg
