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Product introduction

SHP2 protein degrader-2 (SHP2-D26) is a SHP2 protein PROTAC degrader. SHP2 protein degrader-2 reduces expression level of SHP2 in various cancer cells. In Vitro SHP2 protein degrader-2 (SHP2-D26) achieves excellent degradation of SHP2 with the DC 50 (the concentration where 50% of the protein has been degraded) values of 2.6 nM and 6.0 nM for MV4;11 and KYSE520 cells, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

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Chinese name

SHP2 protein degrader-2

English name

SHP2 protein degrader-2

Chinese alias

SHP2蛋白降解剂-2

English alias

CAS number

2740582-16-3

molecular formula

C56H79ClN12O6S2

molecular weight

1115.89 g/mol

Exact mass

≥98%

PSA

Logp

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