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Product introduction
STING agonist-3, extracted from patent WO2017175147A1 (example 10), is a selective and non-nucleotide small-molecule STING agonist with a pEC 50 and pIC 50 of 7.5 and 9.5, respectively. STING agonist-3 has durable anti-tumor effect and tremendous potential to improve treatment of cancer. In Vitro STING agonist-3 exhibits a pEC 50 value of 7.5 in activation of STING in cells, this assay is determined using a luciferase reporter assay in human embryonic kidney cells (HEK293T) co-transfected with plasmids expressing STING and the enzyme firefly luciferase driven by the interferon stimulated response element promoter. ?\nSTING agonist-3 exhibits a pIC 50 value of 9.5 in FRET assay. This is a competition binding assay which aims to determine the binding potency of molecules to the C-terminal Domain (CTD) of human STING. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
Chinese name
STING agonist-3
English name
STING agonist-3
Chinese alias
STING 激动剂-3
English alias
-
CAS number
2138299-29-1
molecular formula
C37H42N12O6
molecular weight
750.81 g/mol
Exact mass
≥99%
PSA
245.000 Ų
Logp
1.600
Technical Documents
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STING agonist-3 5mg

STING agonist-3 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg; ≥99%.

item number:S649178-5mg
Product model:5mg
level: 5mg; ≥99%
Lead Time:30days
sold 855 Items
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5mg

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