- Treatment： EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.
- Hazard summary： 诱导药物代谢酶。[ChemIDplus] 皮肤和强眼刺激物；[Alfa Aesar MSDS] 参见多溴联苯。
- exposure pathway： 口服 (L628); 吸入 (L628); 经皮 (L628)
- Harmful effect： 皮肤毒素 - 氯痤疮。
- Toxicity summary： PBBs的毒性确切机制因具体同系物而异。据信，主要的相互作用涉及芳基烃受体（AhR）。PBBs与AhR结合并激活它，进而启动一系列基因的转录上调，影响生化与内分泌途径、细胞周期调控、形态发生、氧化应激反应以及其他各种过程。这导致了PBBs的多种毒性反应特征。一些已知的诱导基因包括细胞色素P-450依赖性单加氧酶CYP1A1和CYP1A2。(L628)
- Regulatory information： REACH限制物质：限制条件文件：PDF链接
- Health Effects： PBB暴露可能导致体重减轻、皮肤疾病（如痤疮）、神经和免疫系统影响，以及对肝脏、肾脏和甲状腺的影响。(L628)
- Symptoms and Signs： PBB暴露的症状可能包括恶心、腹痛、食欲不振、关节痛、疲劳和虚弱。(L629)
- Minimum Risk Level： 急性经口：0.01 mg/kg/天 (L134)
- Other safety information： 化学品评估：PEC / SN / 其他评估 - 多溴阻燃剂(PBFRs)：健康与环境
- Hazard categories and classifications： 水生慢性1 (86.8%)
- Carcinogen Classification： 2A，可能对人类致癌。(L135)
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Research chemical CAS 92-86-4 98% 25g
Yuanye Research chemical CAS 92-86-4 98% 25g, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
