Saxagliptin hydrate是一种有效，选择性，可逆，竞争性和具有口服活性的二肽基肽酶 4 (DPP-4) 抑制剂。可用于 2 型糖尿病的研究。 Saxagliptin: A Long-Acting Dipeptidyl Peptidase-4 (DPP-4) Enzyme Inhibitor Saxagliptin is a long-acting dipeptidyl peptidase-4 (DPP-4) enzyme inhibitor which is a new class of anti-hyperglycemic agents. Released into the small intestine in response meals, incretins such as Glukagon-like peptide-1 (GLP-1) and glucose-dependent insulin tropic polypeptide (GIP) are known to be gastrointestinal hormones that promote insulin secretion and suppress Glukagon secretion in a glucose concentration-dependent manner. Saxagliptin inhibits the activity of DPP-4 that degrades and inactivates GLP-1 and GIP. Through this inhibition, saxagliptin increases the blood concentration of active GLP-1, and exerts its hypoglycemic effect through increasing insulin secretion and reducing Glukagon secretion. (The product is for research purpose only.)