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Product introduction
SGI-1776 free base是一种新型的,ATP竞争性的Pim1抑制剂,IC50为7 nM,比作用于Pim2和Pim3选择性分别高50和10倍,作用于Flt3和haspin也有效。A potent apoptotic that targets Pim and FLT3 in AML and CLL cells. SGI-1776 is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin A potent apoptotic that targets Pim and FLT3 in AML and CLL cells.
Chinese name
SGI-1776 游离碱, FMS 相关受体酪氨酸激酶 3 抑制剂
English name
SGI-1776 free base
Chinese alias
-
English alias
N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[2,1-f]pyridazin-6-amine | Imidazo[1,2-b]pyridazin-6-amine, N-[(1-methyl-4-piperidinyl)methyl]-3-[3-(trifluoromethoxy)phenyl]- | NSC800883 | NSC-800883 | SB19298 | AC-28432 | N-((1-Me
CAS number
1025065-69-3
molecular formula
C20H22F3N5O
molecular weight
405.42 g/mol
Exact mass
-
PSA
54.700 Ų
Logp
4.300
Technical Documents
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SGI-1776 free base 10mM in DMSO 1ml

SGI-1776 free base 10mM in DMSO 1ml Macklin 1025065-69-3, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number:S796289-1ml
Product model:1ml
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Lead Time:30days
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