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Product introduction

Lomibuvir (VX-222, VCH-222)是一种新型的，有效的，选择性的HCV聚合酶抑制剂，IC50为0.94-1.2 μM，作用于突变型M423T效果低15.3倍，作用于突变型I482L效果低108倍。Phase 2。 Applications： In HCV replicon cells, VX-222 dose-dependently increases IFN-β promoter activity by 5.0-fold and inhibits HCV activity with EC50 and EC90 values of 0.3 and 12 nM, respectively. Also, VX-222 rescues the Sendai virus-activated Rig-I pathway due to the inhibition of viral replication.

Specs ⸢ View details ⸥

Chinese name

VX-222（VCH-222,Lomibuvir）,非核苷抑制剂

English name

VX-222 (VCH-222, Lomibuvir)

Chinese alias

English alias

AS-19557 | 1026785-55-6 (or 1026785-59-0) | NCGC00386146-02 | SCHEMBL15498313 | VCH222 | VCH-222 | s1480 | VX-222 (VCH-222, Lomibuvir) | EINECS 202-403-9 | KBio3_002752 | LOMIBUVIR [INN] | 5-(3,3-dimethyl-but-1-ynyl)-3-[(cis-4-hydroxy-cyclohexyl)-(trans-4

CAS number

1026785-59-0

molecular formula

C25H35NO4S

molecular weight

445.63 g/mol

Exact mass

≥99%

PSA

106.000 Å²

Logp

5.900

Technical Documents

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Research chemical CAS 1026785-59-0 ≥99% 1mg

Name: Research chemical CAS 1026785-59-0 ≥99% 1mg
Brand: 源叶
SKU: S80031-1mg

Yuanye Research chemical CAS 1026785-59-0 ≥99% 1mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：S80031-1mg

Product model：1mg

level： ≥99% 1mg

Lead Time：30days

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Research chemical CAS 1026785-59-0 ≥99% 1mg

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