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Product introduction
GANT61 (NSC 136476)是一种GLI1及GLI2诱导的转录抑制剂,抑制hedgehog,在表达GLI1的HEK293T细胞中IC50为5 μM,选择性作用于其他通路,如TNF和糖皮质激素受体基因的转录。GANT61在LX-2细胞中可诱导凋亡并激活保护性自噬。 GANT 61 是靶向Hedgehog/GLi通路的 Gli1 和 Gli2 抑制剂。 Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Chinese name
GANT 61,GLI1和2抑制剂
English name
GANT 61
Chinese alias
2,2'-[[二氢-2-(4-吡啶基)-1,3-(2H,4H)-嘧啶二基]双(亚甲基)]双[N,N-二甲基苯胺 | 2,2'-[[二氢-2-(4-吡啶基)-1,3(2H,4H)-嘧啶二基]双(亚甲基)]双(N,N-二甲基苯胺)
English alias
NSC 136476 | GANT61 | NCIStruc1_001747 | NCGC00014352-03 | GANT61(NSC 136476) | CHEBI:94276 | DTXSID50329591 | GANT 61(NSC 136476) | 2,2''-(2-(pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)-diyl)bis(methylene)bis(N,N-dimethylaniline) | 2,2'-(2-(pyridin-4-yl)di
CAS number
500579-04-4
molecular formula
C27H35N5
molecular weight
429.61 g/mol
Exact mass
≥98%
PSA
25.900 Ų
Logp
4.200
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MedMol GANT61 99% 10mg

MedMol GANT61 99% 10mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S80748-10mg
Product model:10mg
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Lead Time:30days
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