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Product introduction
AZD5363是各种AKT亚型抑制剂,IC50 Capivasertib (AZD5363)有效抑制Akt(Akt1/Akt2/3)的所有亚型,在无细胞试验中IC50为3 nM/8 nM/8 nM,对P70S6K/PKA也具有相似的抑制效果,而对ROCK1/2抑制活性较低。Phase 2。 AZD5363 potently inhibits all isoforms of Akt(Akt1/Akt2/Akt3) with IC50 of 3 nM/8 nM/8 nM in cell-free assays, similar to P70S6K/PKA and lower activity towards ROCK1/2.
Chinese name
AZD5363,泛泛AKT抑制剂, 丝氨酸/苏氨酸蛋白激酶 AKT 抑制剂
English name
AZD5363
Chinese alias
-
English alias
AZC5363 | DB12218 | J-514447 | s8019 | NCGC00345795-04 | 4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)piperidine-4-carboxamide | Capivasertib (AZD5363) | Trifluoromethane, refrigerated liquid [UN3136] [Nonflammable ga
CAS number
1143532-39-1
molecular formula
C21H25ClN6O2
molecular weight
428.92 g/mol
Exact mass
-
PSA
120.000 Ų
Logp
1.7
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Research chemical 97% 5mg

Research chemical 97% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S81216-5mg
Product model:5mg
level: 97% 5mg
Lead Time:30days
sold 220 Items
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