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Product introduction
Information ONO-4059 analogue ONO-4059 analogue (ONO-WG-307) is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1. Targets BTK 23.9 nM In vitro In TMD-8 cells, ONO-4059 inhibits cell growth with IC50 of 3.59 nM, and induces cell apoptosis. The combination of of ONO-4059 with doxorubicin, etoposide, vincristine or dexamethasone causes the increased apoptosis ratio.
Chinese name
ONO-4059类似物
English name
ONO-4059 analogue
Chinese alias
-
English alias
ONO-WG-307(S)-9-(1-acryloylpiperidin-3-yl)-6-amino-7-(4-phenoxyphenyl)-7H-purin-8(9H)-one
CAS number
1351635-67-0
molecular formula
C25H24N6O3
molecular weight
456.5 g/mol
Exact mass
≥98%
PSA
105.000 Ų
Logp
3.38
Technical Documents
「No technical documents」
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Research chemical ≥98% 1mg

Research chemical ≥98% 1mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S81295-1mg
Product model:1mg
level: ≥98% 1mg
Lead Time:30days
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