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Product introduction
AZD-3463是ALK/IGF1R抑制剂。 AZD-3463 (ALK/IGF1R inhibitor) 是一种ALK/IGF1R 抑制剂,对 ALK 作用的 Ki 值为 0.75 nM。AZD-3463 可诱导神经母细胞瘤细胞凋亡 (apoptosis) 和自噬 (autophagy)。 AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also inhibits IGF1R with equivalent potency.
Chinese name
N-[4-(4-氨基-1-哌啶基)-2-甲氧基苯基]-5-氯-4-(1H-吲哚-3-基)-2-嘧啶胺, ALK 受体酪氨酸激酶抑制剂
English name
AZD3463
Chinese alias
-
English alias
BCP07685 | Q27074737 | CI 37550 | DTXSID50717792 | HMS3653G05 | N-(4-(4-Aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine | BDBM192752 | NCGC00351596-09 | N-(4-(4-aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3
CAS number
1356962-20-3
molecular formula
C24H25ClN6O
molecular weight
448.95 g/mol
Exact mass
-
PSA
92.100 Ų
Logp
4.200
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MedMol AZD3463 98% 5mg

MedMol AZD3463 98% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:S81297-5mg
Product model:5mg
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Lead Time:30days
sold 82 Items
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