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Product introduction

Fisogatinib (BLU-554)是一种有效的、高度选择性的、具有口服活性的FGFR4抑制剂，IC50为5 nM。对FGFR1-3的IC50范围为624-2203 nM。 Information Fisogatinib (BLU-554) Fisogatinib (BLU-554) is a potent, highly-selective, oral FGFR4 inhibitor with an IC50 value of 5 nM. The IC50s for FGFR1-3 is 624-2203 nM. Targets FGFR4 (Cell-free assay) 5 nM In vitro BLU-554 exploits a unique interaction with FGFR4 to confer potency and selectivity In vivo BLU-554 is well tolerated in these tumor models. Administration of BLU-554 induces tumor regression in liver cancer models.

Specs ⸢ View details ⸥

Chinese name

Fisogatinib (BLU-554), 成纤维细胞生长因子受体 4 抑制剂

English name

Fisogatinib (BLU-554)

Chinese alias

非索替尼 (BLU-554)

English alias

AC-29871 | AS-55934 | BB160379 | BDBM50575072 | BLU554 | BLU-554 | 4-Hydroxy-8-methoxyquinoline-3-carboxylic acid ethyl ester, AldrichCPR | GTPL10220 | InChI=1/C13H10O3/c14-12-7-5-10(6-8-12)9-1-3-11(4-2-9)13(15)16/h1-8,14H,(H,15,16 | M0986 | N-[(3S,4S)-3-

CAS number

1707289-21-1

molecular formula

C24H24Cl2N4O4

molecular weight

503.38 g/mol

Exact mass

PSA

94.600 Å²

Logp

4.229

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MedMol BLU-554 99% 1mg

Name: MedMol BLU-554 99% 1mg
Brand: MedMol
SKU: S81395-1mg

MedMol BLU-554 99% 1mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：S81395-1mg

Product model：1mg

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Lead Time：30days

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MedMol BLU-554 99% 1mg

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