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Product introduction

产品介绍 BX471 (ZK-811752) 是选择性，非多肽的 CCR1 拮抗剂，Ki 值为 1 nM，对其选择性是对 CCR2，CCR5 和 CXCR4 的 250 倍。 Product Application BX471 has been used in chemotaxis assay to study the responses of HEK293 cells expressing human C-C motif chemokine receptor 1 (CCR1) to CC motif ligand 3 (CCL3)-induced cell migration. It has also been used as a CCR1 inhibitor to assess the effects of CCR1 on the migration and epithelial-mesenchymal transition (EMT).

Specs ⸢ View details ⸥

Chinese name

BX 471,CCR1拮抗剂, CCR1 拮抗剂

English name

BX 471

Chinese alias

(R)-1-[5-氯-2-[2-[4-(4-氟苄基)-2-甲基哌嗪-1-基]-2-氧代乙氧基]苯基]脲 | (2R)-1-[[[2-[(氨基羰基)氨基] -4-氯苯氧基]乙酰基] -4-[(4-氟苯基)甲基] -2-甲基哌嗪

English alias

BX471 | BX-471 | BX-471 free base | BX 471 | (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea | ZK-811752 | [5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]phenyl]urea | BX-741

CAS number

217645-70-0

molecular formula

C21H24ClFN4O3

molecular weight

434.89 g/mol

Exact mass

PSA

87.900 Å²

Logp

2.500

Technical Documents

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Research chemical 95% 10mg

Name: Research chemical 95% 10mg
Brand: 上海源叶
SKU: S84448-10mg

Research chemical 95% 10mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：S84448-10mg

Product model：10mg

level： 95% 10mg

Lead Time：30days

sold 774 Items

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Research chemical 95% 10mg

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