阿维菌素B1a是一种大环内酯，构成了用于控制牲畜寄生线虫的抗蠕动阿维菌素的大部分。阿维菌素B1a还充当杀虫剂和杀螨剂。阿维菌素在商业上用作动物健康，农业和人类感染中的抗寄生虫剂。研究表明，它可以激活和抑制哺乳动物脑中的GABA | A |Rα1（γ-氨基丁酸A）受体功能。 Avermectin B1a is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. Avermectin B1a also acts as an insecticide and acaricide. The avermectins are used commercially as antiparasitic agents in animal health, agriculture and human infections. Research shows that it can activate and inhibit GABA|A|Rα1 (gamma-aminobutyric acidA) receptor function in mammalian brain.